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MSAFP screening test
Alpha-fetoprotein (AFP) is a protein that is normally produced by the fetus' liver. AFP is present in the fluid around the fetus (amniotic fluid) and a small amount crosses the placenta and moves into the mother's blood stream. As the baby grows and produces more AFP, the amount in the mother's blood increases. Between weeks 15 and 20 of a pregnancy, a maternal serum alpha-fetoprotein (MSAFP) screen may be offered. It's usually as part of a set of tests, which screen for genetic problems, called the quad screen. The AFP blood test determines how much AFP is in the mother's blood. The other tests measure the levels of other pregnancy hormones, including estriol, human chorionic gonadotropin (HCG), and inhibin A.
Dr. Jeff Livingston reviewed this
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